The method of claim 13 wherein in e), said representation is stored in the database produced by claim 1.ġ5. A method of producing a computer readable database comprising a representation of a compound capable of binding a binding pocket of a ArnB protein, said method comprising a) introducing into a computer program a computer readable database produced by claim 1 b) generating a three-dimensional representation of a binding pocket of said ArnB protein in said computer program c) superimposing a three-dimensional model of at least one binding test compound on said representation of the binding pocket d) assessing whether said test compound model fits spatially into the binding pocket of said ArnB protein and e) storing a representation of a compound that fits into the binding pocket into a computer readable database.ġ4. A method comprising electronic transmission of all or part of the computer readable database produced by claim 1.ġ3. A computer readable database produced by claim 1.ġ2. The method of claim 1, wherein said binding pocket comprises an active site.ġ1. The method of claim 8, wherein said binding pocket further comprises His329, Phe330, and Tyr136 according to the sequence of FIGS. The method of claim 7, wherein said binding pocket further comprises Lys241, and Arg229 according to the sequence of FIGS. The method of claim 6 wherein said binding pocket comprises Trp89, Lys188, Ser183, His185, Glu194, Thr64, Asp160, and His163 according to the sequence of FIGS. The method of claim 1 wherein said binding pocket comprises a binding pocket defined by the structural coordinates of at least three amino acids selected from the group consisting of Trp89, Lys188, Ser183, His185, Glu194, Thr64, Asp160, His163, Lys241, Arg229, His329, Phe330, and Tyr136.ħ. The method of claim 4 wherein said binding pocket further comprises amino acids corresponding to His, Phe, and Tyr.Ħ. The method of claim 2 wherein said binding pocket further comprises amino acids corresponding to Lys, and Arg.ĥ. The method of claim 2 wherein said computer is capable of utilizing or displaying a three-dimensional molecular structure comprising said binding pocket using said structural coordinates.Ĥ. The method of claim 1 wherein said binding pocket comprises amino acids Trp, Lys, Ser, His, Glu, Thr, Asp, and His.ģ. A method of producing a computer readable database comprising the three-dimensional molecular structural coordinates of binding pocket of a ArnB protein, said method comprising a) obtaining three-dimensional structural coordinates defining said protein or a binding pocket of said protein, from a crystal of said protein and b) introducing said structural coordinates into a computer to produce a database containing the molecular structural coordinates of said protein or said binding pocket.Ģ. INTERACTIVE VISUAL ANALYSIS OF CLINICAL EPISODESġ. METHOD FOR DISCRIMINATING BETWEEN OPERATING CONDITIONS IN MEDICAL PUMP System For Genetic Surveillance and Analysis SYSTEM AND METHOD FOR ELECTROSTATIC DISCHARGE TESTING Method for identification and functional characterization of agents which modulate ion channel activityĭetection method, microchemical system using the detection method, signal detection method, thermal lens spectroscopic system, fluorescence detection system, signal detection apparatus, signal detection system, signal detection program, and storage medium Methods and systems for profiling biological systemsįALLING STATE DETERMINATION FOR DATA STORAGE DEVICE Regularization model for electrical resistance mapping
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